Wayne of Gotham by Tracy Hickman

By Tracy Hickman

Males separated via homicide: Thomas, the rebellious general practitioner and inheritor to the huge Wayne empire, and Bruce, his son, whose lifestyles is ceaselessly altered through witnessing his parents' homicide. The slaying of Thomas and Martha Wayne is the torturous aspect on which Bruce turns to turn into Batman.

The darkish Knight's dossier at the case has lengthy been closed, the rules of Bruce Wayne's mystery lifestyles safe within the easy genesis of a mugging long gone horribly wrong.

These foundations are shaken, besides the fact that, while an unforeseen visitor invades the grounds of Wayne Manor, elevating questions about the development that ended the lives of the mum he enjoyed and the daddy he worshipped, and sparked his unquenchable force to guard and avenge.

To realize his genuine relatives heritage, Batman needs to face down outdated foes, his basically confidant, and the evil center of Arkham Asylum, and shoulder the recent burden of a depressing legacy.

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H. NUGTEREN and H. VONKEMAN Enzymatic conversion of all-cis-polyunsaturated fatty acids into prostaglandins. Nature. 203: 839-841. 1964. 14Carbon labelled homo--y-linolenic acid was incubated with homogenates of sheep seminal vesicles. The reaction products contained radiolabelled PGE 1 . The enzyme system was also able to convert other straight chain, all-cis-polyunsaturated (18 and 19 carbon) fatty acids into the corresponding nor-prostaglandins. The nor-prostaglandins had very little biological activity.

Saturation of the 11 13 double bond and oxidation of the secondary alcohol group at C-15. In swine lung only the latter transformation occurs. To study this reaction more closely, a purified enzyme was prepared from swine lung. It could be shown that the enzyme was specific for the hydroxyl group at C-15 in the prostaglandins and could thus be named 15-hydroxyprostaglandin dehydrogenase. NAD+ but not NADP+ served as co-factor. The possible use of this enzyme in a sensitive and specific assay for prostaglandins is being investigated.

Authors) 0346 0165 RYHAGE, R. and B. SAMUELSSON The origin of oxygen incorporated during the biosynthesis of prostagland in E I Biochemical and Biophysical Research Communications. 19: 279·282. 1965. The origin of the oxygen incorporated during the formation of PGE I from dihomo-),-linolenic acid was studied by incubating sheep seminal vesicle homogenates with arachidonic acid in an 18 0 environment. The PGE I produced was analyzed by mass spectrometry in conjunction with gas chromatography. The results clearly show that the oxygens of the 2 hydroxyl groups come from oxygen gas, but this study does not allow conclusions to be drawn about the origin of the keto oxygen.

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